February 13, 2019, MedPage Today  

Treatment with direct-acting antivirals (DAAs) for hepatitis C virus (HCV) was associated with a "rapid and significant" decrease in risk for all-cause mortality and hepatocellular carcinoma (HCC), a French prospective study found. But the study could not clarify the long-term effects of these agents on liver decompensation. 

Read more.

February 12, 2019, MedPage Today 

Nonsuspicious adnexal masses had a low risk of malignancy, and many of the lesions resolved spontaneously, according to a large prospective study of conservative management. During a median follow-up of 27 months, fewer than 1 percent of 1,919 patients had an invasive malignancy or borderline tumor at surgery. Torsion and cyst rupture also occurred in fewer than 1 percent of cases. 

Read more.

February 11, 2019, Endorcine Today 

The risk for developing a "more aggressive" form of breast cancer is higher among women with type 2 diabetes compared with women without diabetes, according to findings published in Diabetes Care. Use of insulin analogues did not increase risk for more aggressive breast cancers, according to researchers. 

Read more.

February 11, 2019, Medscape

Robotic mastectomy for invasive breast cancer was performed for the first time in the United States last year, but the move toward this surgical approach ground to a halt soon afterward. The first such operation was performed in September 2018 by Stephen Chagares, MD, at the Monmouth County Medical Center in Long Branch, New Jersey.

Read more.

February 11, 2019, Aleece Fosnight, APAOG President 
via National Coalition for Sexual Health and Healthy Teen Network  

The National Coalition for Sexual Health is sharing HPV resources from Healthy Teen Network related to HPV education in the form of a short video, "HPV: Not Too Late."

From Healthy Teen Network : "Want to spread the word that it’s not too late for young adults to get the HPV vaccine? We’ve prepared this social media kit to make it easy to share our short video, HPV: Not Too Late."  

APAOG will be sharing posts on our social media page throughout the remainder of February and encourage you to do the same!

Click here to view the information on the Healthy Teen Network website, including suggested social media posts, hashtags and graphics! These resources are fantastic ways to integrate into your practice regarding HPV education.  

February 7, 2019, MedPage Today 

A biosimilar to trastuzumab (Herceptin) demonstrated noninferiority versus the branded drug in a randomized trial of patients with metastatic HER2-positive breast cancer.

Treatment with Pfizer's biosimilar PF-05280014 plus paclitaxel led to objective responses in 62.5% of patients with metastatic HER2-positive breast cancer compared with 66.5% for European-sourced (EU) trastuzumab and the taxane, a difference that met statistical requirements for noninferiority. The two treatment groups had virtually identical progression-free survival (PFS), as reported in the British Journal of Cancer(BJC).

February 7, 2019, Endocrine Today 

Pregnant women who incorporate more vitamin C into their diets are at lower risk for developing gestational diabetes than those with insufficient or even adequate dietary vitamin C intake, according to findings published in Clinical Nutrition. 

Read more.

February 7, 2019, University of Helsinki via ScienceDaily 

Researchers in Finland have discovered a drug combination that collaborates with the cancer cells' own MYC oncoprotein, which in large quantities causes self-destruction of the cancer cells. When this combination is enhanced with immune system-boosting anti-PD-1 therapy, a more effective and long-lasting therapeutic effect can be seen in mice. These findings pave the way for new treatment combination strategies to harness the body's natural defenses to fight cancer.  

Read more.

February 4, 2019, MedPage Today  

A relatively fast outpatient procedure helped infertile women become pregnant — without the need for pills or in vitro fertilization, researchers said here. Using micro-catheters and a 0.018-inch guide-wire, physicians can perform proximal fallopian tube recanalization in less than the time it takes to watch a feature length movie, reported Jeff Wang, BS, a fourth-year medical student at Chicago Medical School. 

Read more.

January 31, 2019, MedPage Today 

Higher levels of stromal tumor infiltrating lymphocytes (sTILs) at diagnosis of early triple-negative breast cancer (TNBC) had a significant association with improved disease-free survival (DFS) and overall survival, data for more than 2,000 patients showed. Each 10 percent increment in baseline sTILs correlated with a 13 percent reduction in the hazard ratio for invasive disease-free survival (iDFS), a 17 percent reduction in hazard for distant (d)DFS, and a 16 percent reduction in the hazard for overall survival (OS).  

Read more.